How do you use Computers to develop ...

[jefk]

do you (Carl Bicknell) play 1.e4 or d4 ?
Or 1.Nf3 maybe ?

Developing a repertoire with Aquarium is not something you do in a few days, and i wouldn't recommend it to anybody, that is ordinary chess players. Also for you i have some questions,

1) do you also played complete engine games after the openings phase (it should be possible to convert an Aquarium to a .ctg book and use that on Playchess in the engine room, i haven't tried that myself that).
Some time (about two months) ago we discussed opening books in this forum and a formula was given how to combine engine eval and percentage result (from real games, preferably standard timing ofcourse). That makes sense, in some positions against Sicilian K9 gives a slight advantage for White, nevertheless such games often end in a draw i noticed.

2) despite using Aquarium i presume you sometimes make opening choices ? for example in a d4 repertoire there are several possibilities, playing against a Slav (or others), or choosing for a Catalan setup.
It makes no sense comparing the eval of such openings because with best defense by Black, White cannot win, thus in the end the difference between the (end)eval of the opening are not more than eg one percent -of a pawn- different. Also for practical reasons, depending on rating, making a practical repertoire choice, is recommended. For Black, avoiding the Sicilian, until you are about 1900 rating, and only going for Catalan with White above 1800 or so, i would suggest.

3) have you looked at GM openings books ? For example the Avrukh theory about the Catalan ? Or the theory about the Slav (there are two books by Sakaev but they are hard to read). Then there are two quite recent books (one by Kaufman) about the anti-Gruenfeld. Also a recent book about Sicilian (mainly poisoned pawn) in the Najdorf is interesting.

NB i've done similar things as you in opening analysis, although not using Aquarium (yet) but an old version with Bookbuilder(3.6) together with some other tools (mainly Chessbase, and/or Chesspartner); for average chess players i've written down a repertoire with several options (1.e4, gambits, or 1.d4, excluding Catalan), and now discussed the method (similar to yours) how i arrived at this repertoire at my blog:
www.superchess.blogspot.com

jef